Description

(1S)Cyclopropyl(4-Methylphenyl)Methylamine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its value lies in providing a stereochemically defined, functionalized core structure essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the cyclopropyl and aromatic motifs contribute to biological activity.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for studying biological pathways and protein interactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex specialty chemicals and performance materials.

Basic Information

Product Name	(1S)Cyclopropyl(4-Methylphenyl)Methylamine Hydrochloride
CAS No.	1391449-52-7
Molecular Formula	C12H17N·HCl
Molecular Weight	211.73 g/mol
Synonyms	(1S)-1-Cyclopropyl-1-(4-methylphenyl)methanamine hydrochloride; (S)-1-(4-Methylphenyl)-1-cyclopropylmethanamine hydrochloride; (S)-α-Cyclopropyl-4-methylbenzylamine hydrochloride; (S)-1-(p-Tolyl)cyclopropanemethylamine hydrochloride; (S)-CPMA HCl; (S)-Cyclopropyl(p-tolyl)methylamine hydrochloride; (1S)-1-(4-Methylphenyl)-1-cyclopropanemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1S)Cyclopropyl(4-Methylphenyl)Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, impurity profile, and residual solvents is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.