Description

(1S)-1-(2-Ethoxyphenyl)Butylamine Hydrochloride is a high-purity chiral amine derivative, specifically the (S)-enantiomer, offered as a stable hydrochloride salt. This compound serves as a critical chiral building block and intermediate in the synthesis of advanced pharmaceutical agents and fine chemicals. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of enantiomerically pure active pharmaceutical ingredients (APIs) and other high-value specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly where stereochemistry is crucial for biological activity.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of enantiomerically pure pesticides and herbicides.
• Ligand Synthesis: Precursor for the preparation of chiral ligands used in metal-catalyzed transformations.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic & Industrial R&D: Employed in chemical research exploring new synthetic methodologies and structure-activity relationships.

Basic Information

Item	Details
Product Name	(1S)-1-(2-Ethoxyphenyl)Butylamine Hydrochloride
CAS No.	1391447-01-0
Molecular Formula	C12H20ClNO
Molecular Weight	229.75 g/mol
Synonyms	(S)-1-(2-Ethoxyphenyl)butan-1-amine hydrochloride; (S)-1-(2-Ethoxyphenyl)butylamine HCl; (S)-α-Ethyl-2-ethoxybenzenemethanamine hydrochloride; (1S)-1-(2-Ethoxyphenyl)-1-butanamine hydrochloride; (S)-2-Ethoxy-α-ethylbenzylamine hydrochloride; (S)-1-Amino-1-(2-ethoxyphenyl)butane hydrochloride; (S)-NSC 403179 hydrochloride
EINECS	Contact for details

Quality Control

Our (1S)-1-(2-Ethoxyphenyl)Butylamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality management system supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.