Description

(1S)-1-(3-Fluorophenyl)Pentylamine Hydrochloride is a high-purity chiral amine derivative, specifically designed for advanced chemical synthesis and research applications. This compound matters as a critical chiral building block or intermediate, enabling the development of novel pharmaceuticals and fine chemicals with precise stereochemistry. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric synthesis, medicinal chemistry, and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or metabolic disorder targets.
• Asymmetric Synthesis: Serves as a chiral amine precursor or resolving agent in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Medicinal Chemistry & SAR Studies: Used in structure-activity relationship (SAR) studies to explore the impact of the fluorophenylpentylamine scaffold on biological activity and selectivity.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for the production of complex chiral molecules.
• Agrochemical Research: Potential intermediate in the synthesis of novel chiral herbicides, fungicides, or plant growth regulators.
• Ligand & Catalyst Preparation: Can be utilized for the synthesis of chiral ligands or organocatalysts used in enantioselective transformations.

Basic Information

Product Name	(1S)-1-(3-Fluorophenyl)Pentylamine Hydrochloride
CAS No.	1391446-42-6
Molecular Formula	C11H17ClFN
Molecular Weight	217.71 g/mol
Synonyms	(S)-1-(3-Fluorophenyl)pentan-1-amine hydrochloride; (1S)-1-(3-Fluorophenyl)-1-pentanamine hydrochloride; (S)-3-Fluoro-α-pentylbenzenemethanamine hydrochloride; (S)-1-Amino-1-(3-fluorophenyl)pentane hydrochloride; (S)-α-Pentyl-3-fluorobenzylamine hydrochloride; (S)-NSC 781406 hydrochloride; (1S)-1-(3-Fluorophenyl)pentylamine HCl
EINECS	Contact for details

Quality Control

Our (1S)-1-(3-Fluorophenyl)Pentylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.