Description

(R)-1-(6-Chloropyridin-3-Yl)Ethanamine Hcl is a high-purity chiral amine building block, specifically the hydrochloride salt of the (R)-enantiomer. This compound is a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals, where stereochemical purity is paramount for efficacy and safety. It is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel, optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel, stereoselective pesticides and herbicides, where the specific enantiomer can significantly impact biological activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Chemical Research & Development: A valuable building block for medicinal chemistry programs and process chemistry optimization in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific optical activity.

Basic Information

Product Name	(R)-1-(6-Chloropyridin-3-Yl)Ethanamine Hydrochloride
CAS No.	1391444-87-3
Molecular Formula	C7H10Cl2N2
Molecular Weight	193.07 g/mol
Synonyms	(R)-1-(6-Chloro-3-pyridinyl)ethanamine hydrochloride; (R)-α-Methyl-6-chloro-3-pyridinemethanamine hydrochloride; (R)-1-(6-Chloropyridin-3-yl)ethan-1-amine hydrochloride; (R)-6-Chloro-3-(1-aminoethyl)pyridine HCl; (R)-Enantiomer of 1-(6-Chloropyridin-3-yl)ethanamine HCl; (R)-CPEA HCl; (R)-1-(6-Chloro-3-pyridyl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(6-Chloropyridin-3-Yl)Ethanamine HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.