Description

(R)-3-(1-Aminoethyl)Aniline Hydrochloride is a high-purity chiral amine building block essential for the synthesis of enantiomerically pure compounds. Its value lies in providing a defined stereocenter for constructing complex molecules with high biological specificity. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for developing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel, enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific herbicides, fungicides, and insecticides where the (R)-enantiomer confers the desired biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex fine chemicals and specialty materials requiring a specific (R)-configured benzylamine moiety.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new chemical entities in life sciences.

Basic Information

Product Name	(R)-3-(1-Aminoethyl)Aniline Hydrochloride
CAS No.	1391439-77-2
Molecular Formula	C8H13ClN2
Molecular Weight	172.65 g/mol
Synonyms	(R)-3-(1-Aminoethyl)benzenamine hydrochloride; (R)-1-(3-Aminophenyl)ethylamine hydrochloride; (R)-m-Amino-α-methylbenzylamine hydrochloride; (R)-3-(1-Aminoethyl)phenylamine HCl; (R)-3-Amino-α-methylbenzylamine hydrochloride; (R)-1-(3-Aminophenyl)ethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-(1-Aminoethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess (ee), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.