Description

(2R)-2-Amino-2-(4-Methylphenyl)Ethan-1-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in creating novel therapeutics and advanced organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a chiral precursor or resolving agent in catalytic and stoichiometric asymmetric synthesis to induce stereoselectivity.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and synthesis of novel peptide-like molecules for drug discovery.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for metal-catalyzed reactions or organocatalysts.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(2R)-2-Amino-2-(4-Methylphenyl)Ethan-1-Ol Hydrochloride
CAS No.	1391439-16-9
Molecular Formula	C9H14ClNO
Molecular Weight	187.66 g/mol
Synonyms	(R)-2-Amino-2-(p-tolyl)ethanol hydrochloride; (R)-2-Amino-2-(4-methylphenyl)ethanol hydrochloride; (2R)-2-Amino-2-(4-methylphenyl)ethan-1-ol hydrochloride; (R)-p-Methylphenylglycinol hydrochloride; (R)-4-Methylphenylglycinol hydrochloride; (R)-Hpg(4-Me)-OH•HCl; (R)-1-(4-Methylphenyl)-2-aminoethanol hydrochloride
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-(4-Methylphenyl)Ethan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.