Description

(R)-2-(2-Methoxyphenyl)Piperidine Hydrochloride CAS NO 1391438-83-7 is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical research and development. Its value lies in its role as a versatile intermediate for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel therapeutic agents with high stereoselectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel central nervous system (CNS) drugs, analgesics, and other therapeutic agents.
• Asymmetric Synthesis: Used as a chiral ligand precursor or resolving agent in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the synthesis of enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Academic & Institutional Research: Utilized in universities and research institutes for studying chiral pharmacology and developing new synthetic methodologies.
• Process Chemistry: Scaled for use in pilot plants and commercial manufacturing of advanced pharmaceutical intermediates under GMP conditions.

Basic Information

Product Name	(R)-2-(2-Methoxyphenyl)Piperidine Hydrochloride
CAS No.	1391438-83-7
Molecular Formula	C12H18ClNO
Molecular Weight	227.73 g/mol
Synonyms	(R)-2-(2-Methoxyphenyl)piperidine HCl; (R)-2-(o-Methoxyphenyl)piperidine hydrochloride; (R)-2-(2-Methoxyphenyl)piperidine hydrochloride; (R)-2-(2-Methoxyphenyl)piperidinium chloride; (2R)-2-(2-Methoxyphenyl)piperidine hydrochloride; (R)-o-Methoxyphenylpiperidine hydrochloride; (R)-2-(2-Methoxyphenyl)piperidine HCl salt
EINECS	Contact for details

Quality Control

Our (R)-2-(2-Methoxyphenyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.