Description

(R)-1-(6-Methoxypyridin-3-Yl)Propan-1-Amine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for central nervous system (CNS) and metabolic disease targets.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up the production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Ligand and Catalyst Preparation: Can be utilized in the preparation of chiral ligands for catalytic asymmetric transformations.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	(R)-1-(6-Methoxypyridin-3-Yl)Propan-1-Amine Hydrochloride
CAS No.	1391417-23-4
Molecular Formula	C9H14N2O • HCl
Molecular Weight	202.68 g/mol
Synonyms	(R)-1-(6-Methoxypyridin-3-yl)propan-1-amine hydrochloride; (R)-1-(6-Methoxy-3-pyridinyl)-1-propanamine hydrochloride; (R)-1-(6-Methoxypyridin-3-yl)propylamine hydrochloride; (R)-α-Methyl-6-methoxynicotinylamine hydrochloride; (R)-3-(1-Aminopropyl)-6-methoxypyridine hydrochloride; (R)-6-Methoxy-3-(1-aminopropyl)pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(6-Methoxypyridin-3-Yl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.