Description

(1R)Cyclopropyl(2-Methylphenyl)Methylamine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in advanced organic synthesis. Its defined stereochemistry and stable salt form make it an essential intermediate for creating enantiomerically pure compounds with high pharmacological relevance. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Used in the synthesis of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Ligand Development: Acts as a precursor for the synthesis of chiral ligands used in metal-catalyzed transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Provides a reliable, high-quality starting material for optimizing synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	(1R)Cyclopropyl(2-Methylphenyl)Methylamine Hydrochloride
CAS No.	1391400-95-5
Molecular Formula	C12H17N·HCl
Molecular Weight	211.73 g/mol
Synonyms	(1R)-1-Cyclopropyl-1-(2-methylphenyl)methanamine hydrochloride; (R)-1-(2-Methylphenyl)-1-cyclopropanemethanamine hydrochloride; (R)-α-Cyclopropyl-2-methylbenzylamine hydrochloride; (R)-1-Cyclopropyl-1-(o-tolyl)methanamine hydrochloride; (R)-o-Methyl-α-cyclopropylbenzylamine hydrochloride; (1R)-Cyclopropyl(o-tolyl)methylamine hydrochloride; (R)-CPMA HCl
EINECS	Contact for details

Quality Control

Our (1R)Cyclopropyl(2-Methylphenyl)Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.