Description

(1R)-2-Methyl-1-(4-Methylphenyl)Propylamine Hydrochloride is a high-purity chiral amine salt, a critical building block in advanced organic synthesis. Its defined stereochemistry and stable hydrochloride form make it an essential intermediate for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst and Ligand Preparation: Serves as a starting material for synthesizing chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic and Industrial Research: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(1R)-2-Methyl-1-(4-Methylphenyl)Propylamine Hydrochloride
CAS No.	1391378-45-2
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(1R)-1-(p-Tolyl)-2-methylpropylamine hydrochloride; (R)-1-(4-Methylphenyl)-2-methylpropylamine hydrochloride; (R)-α,2-Dimethyl-4-methylbenzenepropanamine hydrochloride; Dexylamine hydrochloride (related to dextro isomer); (R)-2-Methyl-1-(4-methylphenyl)propan-1-amine hydrochloride; p-Methylamphetamine derivative (chiral); (1R)-α,2-Dimethyl-4-methylbenzeneethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our production of (1R)-2-Methyl-1-(4-Methylphenyl)Propylamine Hydrochloride adheres to stringent quality protocols. Each batch is characterized and tested to ensure identity, purity, and chiral integrity, meeting the exacting standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), assay, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%, Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.