Description

5-Bromo-2,3-Dihydroquinolin-4(1H)-One is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its quinolinone core structure.
• Material Science: Acts as a building block for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Catalyst Ligand Synthesis: Utilized as a starting material for creating novel chiral or achiral ligands used in asymmetric catalysis.
• Academic & Contract Research: Essential for fundamental research in organic chemistry and for contract research organizations (CROs) supporting client discovery programs.

Basic Information

Product Name	5-Bromo-2,3-Dihydroquinolin-4(1H)-One
CAS No.	1391268-61-3
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	5-Bromo-1,2,3,4-tetrahydro-4-oxoquinoline; 5-Bromo-1,2,3,4-tetrahydroquinolin-4-one; 5-Bromo-3,4-dihydro-2H-quinolin-4-one; 5-Bromotetrahydro-4-quinolone; 4(1H)-Quinolinone, 5-bromo-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Dihydroquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.