Description

8-(Trifluoromethyl)-3,4-Dihydro-2H-1-Benzopyran is a high-purity fluorinated benzopyran derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique combination of the benzopyran scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its structural motifs are leveraged to enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for creating specialty chemicals and functional materials with specific optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in methodological studies and as a substrate for developing novel fluorination or cyclization reactions.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Details
Product Name	8-(Trifluoromethyl)-3,4-Dihydro-2H-1-Benzopyran
CAS No.	1391113-02-2
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	8-(Trifluoromethyl)chroman; 3,4-Dihydro-8-(trifluoromethyl)-2H-1-benzopyran; 8-Trifluoromethylchroman; 2H-1-Benzopyran, 3,4-dihydro-8-(trifluoromethyl)-; Chroman, 8-(trifluoromethyl)-; 1391113-02-2
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-3,4-Dihydro-2H-1-Benzopyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.