Description

4-Amino-2-Ethynylphenol is a specialized aromatic compound featuring both an amino and an ethynyl functional group on a phenolic ring, making it a valuable multifunctional building block in advanced organic synthesis. This unique structure provides versatile reactivity for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its phenolic and alkyne functionalities.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Ligand & Catalyst Development: Employed in the creation of novel ligands for metal-organic frameworks (MOFs) and catalysts for asymmetric synthesis.
• Dye & Pigment Research: Functions as an intermediate in the synthesis of advanced organic dyes and functional pigments.
• Academic & Industrial R&D: A crucial reagent for methodological studies in organic chemistry and for exploring new chemical reactions and pathways.

Basic Information

Product Name	4-Amino-2-Ethynylphenol
CAS No.	1391053-48-7
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	2-Ethynyl-4-aminophenol; 4-Amino-2-ethynylphenol; 2-Ethynyl-4-hydroxyaniline; 4-Hydroxy-2-ethynylaniline; Phenol, 4-amino-2-ethynyl-; 4-Amino-2-ethinylphenol; 2-Ethinyl-4-aminophenol
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Ethynylphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.