Description

1-Cyclopropyl-1,4-Dihydro-6-Benzyloxy-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid Benzyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key synthetic precursor in the development of novel fluoroquinolone antibiotics, offering a critical structural framework for medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antimicrobial drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of next-generation fluoroquinolone antibiotic candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize antibacterial potency and pharmacokinetic profiles.
• Process Development: Serves as a reference standard and key material in scaling up API (Active Pharmaceutical Ingredient) manufacturing processes.
• Academic Research: Employed in university and institutional labs for studying quinolone chemistry and developing novel antimicrobial agents.
• Fine Chemical Synthesis: Utilized as a specialized reagent for constructing complex heterocyclic systems in custom synthesis projects.

Basic Information

Product Name	1-Cyclopropyl-1,4-Dihydro-6-Benzyloxy-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid Benzyl Ester
CAS No.	1391052-85-9
Molecular Formula	C31H31N3O4
Molecular Weight	509.60 g/mol
Synonyms	Benzyl 1-cyclopropyl-6-(benzyloxy)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate; 7-Piperazinyl-6-benzyloxy-1-cyclopropyl-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Benzyl Ester; 1-Cyclopropyl-6-benzyloxy-4-oxo-7-piperazinyl-1,4-dihydroquinoline-3-carboxylic Acid Benzyl Ester; Fluoroquinolone Intermediate BA-12; Quinolone Carboxylic Acid Benzyl Ester Derivative; 7-(1-Piperazinyl)-6-(phenylmethoxy)-1-cyclopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic Acid Phenylmethyl Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.