Description

1-Cyclopropyl-1,4-Dihydro-7-Fluoro-6-Hydroxy-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex quinolone core structure. This compound is critical for research and development in the synthesis of novel antibacterial agents, offering a key building block for creating next-generation therapeutics. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on active pharmaceutical ingredient (API) production and antimicrobial innovation.

Application

• Pharmaceutical Intermediate: A key synthon in the research and commercial synthesis of potent fluoroquinolone antibiotic APIs.
• Antimicrobial Research: Serves as a core scaffold for developing new antibacterial compounds targeting DNA gyrase and topoisomerase IV.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to introduce the complex quinolone-carboxylic acid moiety into target molecules.
• Process Development: Employed in scaling up and optimizing manufacturing routes for quinolone-based drugs in pilot plants and production facilities.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory testing of related pharmaceutical products.

Basic Information

Product Name	1-Cyclopropyl-1,4-Dihydro-7-Fluoro-6-Hydroxy-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	1391051-76-5
Molecular Formula	C₁₃H₁₀FNO₄
Molecular Weight	263.22 g/mol
Synonyms	7-Fluoro-6-hydroxy-4-oxo-1-cyclopropyl-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-7-fluoro-6-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1-cyclopropyl-1,4-dihydro-7-fluoro-6-hydroxy-4-oxo-; Fluoroquinolone intermediate; Quinolone carboxylic acid derivative; 7-Fluoro-6-hydroxy-1-cyclopropyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-1,4-Dihydro-7-Fluoro-6-Hydroxy-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.