Description

1,8-Diazaspiro[4.5]Decan-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is primarily sought by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and agrochemical innovators for developing new therapeutic and agrochemical candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in neurological and psychiatric applications.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex spirocyclic and heterocyclic frameworks.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and insecticides with novel modes of action.
• Chemical Biology Probe Development: Used in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Academic & Industrial R&D: Employed in research institutions and corporate R&D centers for exploratory chemistry and process development.

Basic Information

Product Name	1,8-Diazaspiro[4.5]Decan-2-One Hydrochloride
CAS No.	1389313-57-8
Molecular Formula	C8H15ClN2O
Molecular Weight	190.67 g/mol
Synonyms	1,8-Diazaspiro[4.5]decan-2-one, hydrochloride; 2-Oxo-1,8-diazaspiro[4.5]decane hydrochloride; 1,8-Diazaspiro[4.5]decan-2-one HCl; Spirocyclic Piperidine Lactam Hydrochloride; 1-Azaspiro[4.5]decan-8-one hydrochloride (related structure); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,8-Diazaspiro[4.5]Decan-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.