Description

2-Fluoro-5-Trifluoromethyl-3-Nitrobenzoic Acid is a high-value, multi-functional aromatic building block characterized by its unique trifluoromethyl and nitro substituents. This compound is essential for the synthesis of complex molecules, where its fluorine atoms and electron-withdrawing groups are leveraged to modulate biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes, enzyme inhibitors, and fluorinated tags for study and detection.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-5-Trifluoromethyl-3-Nitrobenzoic Acid
CAS No.	1389313-52-3
Molecular Formula	C8H3F4NO4
Molecular Weight	253.11 g/mol
Synonyms	3-Nitro-2-fluoro-5-(trifluoromethyl)benzoic Acid; 2-Fluoro-3-nitro-5-(trifluoromethyl)benzoic Acid; Benzoic acid, 2-fluoro-5-(trifluoromethyl)-3-nitro-; 1389313-52-3; 2-Fluoro-α,α,α-trifluoro-3-nitro-5-toluic Acid
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-5-Trifluoromethyl-3-Nitrobenzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.