Description

1-Benzyl-4,4-Difluorocyclohexan-1-Aminehydrochloride is a high-purity, fluorinated amine hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its unique difluorocyclohexyl scaffold, which is instrumental in modulating the physicochemical and metabolic properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting G-protein-coupled receptors (GPCRs) and enzymes.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the difluorocyclohexyl moiety can enhance biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds or probes used to study biological pathways and protein functions.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with tailored properties like chemical resistance or specific optical characteristics.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthesis in fluorine chemistry.

Basic Information

Product Name	1-Benzyl-4,4-Difluorocyclohexan-1-Aminehydrochloride
CAS No.	1389313-28-3
Molecular Formula	C13H18ClF2N
Molecular Weight	261.74 g/mol
Synonyms	1-Benzyl-4,4-difluorocyclohexan-1-amine hydrochloride; N-Benzyl-4,4-difluorocyclohexanamine hydrochloride; 4,4-Difluoro-N-benzylcyclohexanamine hydrochloride; 1-Amino-1-benzyl-4,4-difluorocyclohexane hydrochloride; (4,4-Difluorocyclohexyl)(phenylmethyl)amine hydrochloride; N-(4,4-Difluorocyclohexyl)-N-benzylamine hydrochloride; 1389313-28-3; Benzyl(4,4-difluorocyclohexyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4,4-Difluorocyclohexan-1-Aminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.