Description

2-Aza-Tricyclo[3.3.1.13,7]Decane-5-Carboxylic Acid Methyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its complex, rigid tricyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics and other specialized drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of novel chemical libraries for high-throughput screening.
• API Development: Used in the research and process development stages for new Active Pharmaceutical Ingredients, especially within the CNS therapeutic area.
• Academic & Industrial R&D: Employed in synthetic organic chemistry research to explore new methodologies and reactions involving constrained amine derivatives.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring high-fidelity, complex intermediates.

Basic Information

Product Name	2-Aza-Tricyclo[3.3.1.13,7]Decane-5-Carboxylic Acid Methyl Ester Hydrochloride
CAS No.	1389264-13-4
Molecular Formula	C11H17NO2·HCl
Molecular Weight	231.72 g/mol (Free base: 195.26 g/mol)
Synonyms	2-Azaadamantane-5-carboxylic acid methyl ester hydrochloride; Methyl 2-azaadamantane-5-carboxylate hydrochloride; 2-Azatricyclo[3.3.1.13,7]decan-5-carboxylic acid methyl ester hydrochloride; 2-Aza-tricyclo[3.3.1.13,7]decan-5-carboxylic acid methyl ester HCl; 2-Azaadamantane-5-methyl carboxylate HCl; Adamantane-derived amine ester hydrochloride; 2-Aza-5-methoxycarbonyladamantane hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aza-Tricyclo[3.3.1.13,7]Decane-5-Carboxylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.