Description

8-Bromo-2,4-dichloro-6-methylquinazoline is a high-purity, multi-functional halogenated quinazoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the quinazoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as semiconductors or light-emitting compounds.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its bromo and chloro substituents.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new reaction pathways involving polyhalogenated heterocycles.

Basic Information

Product Name	8-Bromo-2,4-Dichloro-6-Methylquinazoline
CAS No.	1388055-70-6
Molecular Formula	C9H5BrCl2N2
Molecular Weight	292.96 g/mol
Synonyms	8-Bromo-2,4-dichloro-6-methyl-quinazoline; Quinazoline, 8-bromo-2,4-dichloro-6-methyl-; 2,4-Dichloro-8-bromo-6-methylquinazoline; 6-Methyl-8-bromo-2,4-dichloroquinazoline; 8-Br-2,4-Cl2-6-Me-quinazoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,4-dichloro-6-methylquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation transparency supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat and incompatible materials. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.