Description

2-Chloro-5-Methylquinazoline is a versatile and high-purity organic building block essential for advanced chemical synthesis. This heterocyclic compound serves as a critical intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. Its reactive chloro and methyl substituents make it a valuable precursor for researchers and manufacturers requiring precise molecular architecture for active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development and production of advanced pesticides and herbicides, leveraging the quinazoline core's bioactivity.
• Material Science: Serves as a precursor for the synthesis of specialty chemicals, dyes, and functional organic materials.
• Academic & R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic pathways in organic chemistry.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of complex molecules for clients.

Basic Information

Product Name	2-Chloro-5-Methylquinazoline
CAS No.	1388050-63-2
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	5-Methyl-2-chloroquinazoline; 2-Chloro-5-methyl-quinazoline; Quinazoline, 2-chloro-5-methyl-; 1388050-63-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.