Description

7-Bromo-8-Methyl-3,4-Dihydroquinolin-2(1H)-One is a high-purity, synthetically valuable heterocyclic building block, primarily serving as a key intermediate in advanced pharmaceutical research and development. Its core value lies in enabling the synthesis of complex molecules, particularly for drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new therapeutic compounds.
• Process Chemistry Development: Serves as a key starting material or intermediate in scaling up synthetic routes from laboratory to pilot and commercial production.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides due to its heterocyclic quinoline core.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysts or functional materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	7-Bromo-8-Methyl-3,4-Dihydroquinolin-2(1H)-One
CAS No.	1388050-27-8
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	7-Bromo-8-methyl-1,2,3,4-tetrahydroquinolin-2-one; 8-Methyl-7-bromo-3,4-dihydro-2(1H)-quinolinone; 2(1H)-Quinolinone, 7-bromo-3,4-dihydro-8-methyl-; 7-Bromo-8-methyl-3,4-dihydro-2(1H)-quinolinone; 7-Bromo-8-methyl-1,2,3,4-tetrahydroquinolin-2-one; Tetrahydroquinolinone derivative; Bromomethyl dihydroquinolinone
EINECS	Contact for details

Quality Control

Our 7-Bromo-8-Methyl-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.