Description

4-Oxo-1,2,3,4-Tetrahydroquinoline-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering a unique scaffold for medicinal chemistry research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates with potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and formulation of novel crop protection agents and pesticides.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and fine chemicals.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and advanced organic materials.

Basic Information

Product Name	4-Oxo-1,2,3,4-Tetrahydroquinoline-6-Carbonitrile
CAS No.	1388049-36-2
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	6-Cyano-1,2,3,4-tetrahydro-4-quinolone; 6-Cyano-3,4-dihydro-2H-1,4-benzoxazin-2-one (tautomer); 6-Cyano-4-hydroxyquinoline; 1,2,3,4-Tetrahydro-4-oxoquinoline-6-carbonitrile; Quinoline-6-carbonitrile, 1,2,3,4-tetrahydro-4-oxo-; THQ-6-CN
EINECS	Contact for details

Quality Control

Our 4-Oxo-1,2,3,4-Tetrahydroquinoline-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.