Description

8-Bromo-2,4-Dichloro-6-Methoxyquinazoline is a high-purity halogenated quinazoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its versatile reactivity, serving as a key building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the quinazoline core's biological relevance.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the halogen and methoxy substituents offer tunable biological activity.
• Material Science: Serves as a building block for organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific molecules.
• Academic Research: Utilized in university and institutional labs for methodological development in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	8-Bromo-2,4-Dichloro-6-Methoxyquinazoline
CAS No.	1388026-74-1
Molecular Formula	C9H5BrCl2N2O
Molecular Weight	308.96 g/mol
Synonyms	8-Bromo-2,4-dichloro-6-methoxyquinazoline; 6-Methoxy-8-bromo-2,4-dichloroquinazoline; 2,4-Dichloro-8-bromo-6-methoxyquinazoline; Quinazoline, 8-bromo-2,4-dichloro-6-methoxy-; BDDMQ
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,4-Dichloro-6-Methoxyquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity advanced intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This compound should be considered moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.