Description

Umibecestat CAS NO 1387560-01-1 is a high-purity, small molecule pharmaceutical intermediate and research chemical. This compound is of significant interest in the development of novel therapeutic agents, particularly within the field of neuroscience. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and academic institutions engaged in advanced drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of investigational new drugs targeting specific biological pathways.
• Neuroscience Research: Used as a reference standard or active compound in preclinical studies related to neurological disorders.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and in-vitro testing to evaluate biological activity and mechanism of action.
• API Development: Functions as a key starting material (KSM) or advanced intermediate in the development of Active Pharmaceutical Ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental chemical and pharmacological research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Umibecestat
CAS No.	1387560-01-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CNP520; (S)-2-Amino-3,3-dimethylbutanamide Derivative; BACE Inhibitor CNP520; 5-Chloro-2-((S)-3-methylmorpholino)pyridin-4-yl Derivative; Aβ Production Inhibitor; Amyloid Precursor Protein Cleaving Enzyme Inhibitor; Research Code CNP-520
EINECS	Contact for details

Quality Control

Our Umibecestat is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, NMR, and MS. Quality standards are aligned with cGMP principles for pharmaceutical intermediates, and we support regulatory filings with necessary documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.