Description

cis-4-Cyanocyclohexylamine Hydrochloride, 97% is a high-purity, functionalized cyclohexylamine derivative that serves as a versatile chiral building block in advanced organic synthesis. Its value lies in the combination of a reactive nitrile group and a primary amine, protected as a hydrochloride salt for enhanced stability and handling. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for constructing complex, stereodefined molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with tailored stereochemistry.
• Ligand and Catalyst Development: Precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecules: Used to introduce constrained cyclohexyl backbones and functional handles into peptide analogs and other bioactive scaffolds.
• Material Science Research: Monomer or functional modifier in the synthesis of specialized polymers and advanced materials.
• Chemical Biology Probes: Useful for labeling and cross-linking studies due to its amine reactivity and nitrile functionality.

Basic Information

Product Name	cis-4-Cyanocyclohexylamine Hydrochloride, 97%
CAS No.	1387445-51-3
Molecular Formula	C7H13ClN2
Molecular Weight	160.64 g/mol
Synonyms	cis-4-Aminocyclohexanecarbonitrile Hydrochloride; (1r,4r)-4-Aminocyclohexane-1-carbonitrile Hydrochloride; (1s,4s)-4-Aminocyclohexane-1-carbonitrile Hydrochloride; 4-Cyanocyclohexylamine Hydrochloride (cis-); trans-4-Cyanocyclohexylamine Hydrochloride (isomer); 4-Aminocyclohexyl Cyanide Hydrochloride; 4-Cyano-1-cyclohexanamine Hydrochloride; 1,4-Cyclohexanediamine, 4-cyano-, hydrochloride (cis-)
EINECS	Contact for details

Quality Control

Our cis-4-Cyanocyclohexylamine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation by IR and NMR. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.