Description

6-Bromo-4-[[(2S)-2-Methoxypropyl]Amino]Quinoline-3-Carboxylic Acid is a high-purity, chiral quinoline derivative designed for advanced pharmaceutical research and development. This compound serves as a critical building block (API intermediate) in the synthesis of targeted therapeutic agents, offering researchers precise control over molecular structure and stereochemistry. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), particularly for oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable quinoline scaffold and chiral center.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and target validation.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities for client-specific R&D programs.

Basic Information

Product Name	6-Bromo-4-[[(2S)-2-Methoxypropyl]Amino]Quinoline-3-Carboxylic Acid
CAS No.	1386874-30-1
Molecular Formula	C15H17BrN2O3
Molecular Weight	353.21 g/mol
Synonyms	6-Bromo-4-[(2S)-2-methoxypropylamino]quinoline-3-carboxylic acid; (S)-6-Bromo-4-((2-methoxypropyl)amino)quinoline-3-carboxylic acid; 4-[[(2S)-2-Methoxypropyl]amino]-6-bromoquinoline-3-carboxylic acid; 6-Bromo-4-[(S)-2-methoxypropylamino]quinoline-3-carboxylic acid; 1386874-30-1; UNII-9G7J3H7T3F; 9G7J3H7T3F
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-[[(2S)-2-Methoxypropyl]Amino]Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.