Description

2,7-Diazaspiro[4.5]Decan-3-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• API Synthesis: Serves as a core scaffold in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays and diagnostic tool development due to its reactive amine functionality.
• Academic & Institutional Research: Employed in universities and research institutes for studying spirocyclic compound properties and developing new synthetic methodologies.

Basic Information

Product Name	2,7-Diazaspiro[4.5]Decan-3-One Hydrochloride
CAS No.	1385696-86-5
Molecular Formula	C8H15N2O·HCl
Molecular Weight	192.68 g/mol
Synonyms	2,7-Diazaspiro[4.5]decan-3-one hydrochloride; 3-Oxo-2,7-diazaspiro[4.5]decane hydrochloride; 2,7-Diazaspiro[4.5]decan-3-one HCl; 2,7-Diazaspiro[4.5]decan-3-one monohydrochloride; Spiro[4.5]decan-3-one, 2,7-diaza-, hydrochloride; 1385696-86-5; 2,7-Diazaspiro[4.5]decan-3-one hydrochloride salt
EINECS	Contact for details

Quality Control

Our 2,7-Diazaspiro[4.5]Decan-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.