Description

1-Cbz-1,8-Diazaspiro[4.5]Decane Hydrochloride is a high-purity, protected diazaspirodecane building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly for targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by medicinal chemists and process development scientists within the pharmaceutical and biotechnology industries. The hydrochloride salt form enhances stability and handling for precise synthetic applications.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of novel drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up API (Active Pharmaceutical Ingredient) synthesis under GMP conditions.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Chemical Biology Probes: Useful for creating tool compounds to study biological pathways and protein function.

Basic Information

Product Name	1-Cbz-1,8-Diazaspiro[4.5]Decane Hydrochloride
CAS No.	1385696-68-3
Molecular Formula	C19H27N3O2 • HCl
Molecular Weight	365.90 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-1,8-diazaspiro[4.5]decane hydrochloride; 1-Carbobenzoxy-1,8-diazaspiro[4.5]decane HCl; 1,8-Diazaspiro[4.5]decane-1-carboxylic acid, benzyl ester, hydrochloride; Cbz-1,8-Diazaspiro[4.5]decane HCl; 1-N-Cbz-1,8-Diazaspiro[4.5]decane hydrochloride; Benzyl 1,8-diazaspiro[4.5]decane-1-carboxylate hydrochloride; 1,8-Diazaspiro[4.5]decane-1-carboxylate, benzyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Cbz-1,8-Diazaspiro[4.5]Decane Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.