Description

3-(4-Bromophenyl)Azetidin-3-Amine 2Hcl is a high-purity azetidine derivative, a crucial nitrogen-containing heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Scaffold: Used to introduce the constrained azetidine ring, which can improve metabolic stability, solubility, and binding affinity in lead optimization.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value nitrogen heterocycles.

Basic Information

Item	Detail
Product Name	3-(4-Bromophenyl)Azetidin-3-Amine 2Hcl
CAS No.	1384264-75-8
Molecular Formula	C9H12BrCl2N2
Molecular Weight	308.02 g/mol
Synonyms	3-Amino-3-(4-bromophenyl)azetidine dihydrochloride; 3-(4-Bromophenyl)-3-aminoazetidine hydrochloride (1:2); 3-(p-Bromophenyl)azetidin-3-amine dihydrochloride; 1,1-Dimethylethyl 3-amino-3-(4-bromophenyl)azetidine-1-carboxylate dihydrochloride (precursor related); 3-(4-Bromophenyl)azetidin-3-amine hydrochloride; AZETIDINE, 3-AMINO-3-(4-BROMOPHENYL)-, DIHYDROCHLORIDE
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Bromophenyl)Azetidin-3-Amine 2Hcl is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for research-grade and advanced intermediate chemicals. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to guarantee identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.