Description

4-(tert-Butyl)-1H-Imidazol-2-Amine Hcl is a high-purity, functionalized imidazole derivative, specifically the hydrochloride salt of a 2-aminoimidazole bearing a tert-butyl substituent. This compound is a versatile and critical pharmaceutical intermediate and organic building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting kinase inhibition, anti-inflammatory, and anti-infective pathways.
• Medicinal Chemistry Building Block: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies due to its privileged imidazole scaffold.
• Agrochemical Research: Serves as a core structure for developing new fungicides, herbicides, and plant growth regulators.
• Ligand Synthesis in Catalysis: Employed in the preparation of N-heterocyclic carbene (NHC) precursors and other specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating complex molecules with specific functional group arrays.

Basic Information

Product Name	4-(tert-Butyl)-1H-Imidazol-2-Amine Hcl
CAS No.	1384100-95-1
Molecular Formula	C7H14ClN3
Molecular Weight	175.66 g/mol
Synonyms	2-Amino-4-tert-butyl-1H-imidazole hydrochloride; 4-tert-Butyl-1H-imidazol-2-amine hydrochloride; 4-(1,1-Dimethylethyl)-1H-imidazol-2-amine hydrochloride; 4-(tert-Butyl)-2-imidazolamine hydrochloride; 2-Amino-4-(tert-butyl)imidazole HCl; 4-tert-Butyl-2-aminoimidazole HCl; 4-tert-Butyl-1H-imidazol-2-ylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyl)-1H-Imidazol-2-Amine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.