Description

2-(Prop-2-Yn-1-Yloxy)Ethan-1-Amine Hydrochloride is a specialized organic building block featuring a terminal alkyne and an amine hydrochloride functional group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for applications such as medicinal chemistry, bioconjugation, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for creating molecular scaffolds with specific biological activity.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization studies to introduce alkyne and amine functionalities for structure-activity relationship (SAR) exploration.
• Bioconjugation and Probe Development: The terminal alkyne group enables efficient "click chemistry" reactions (e.g., CuAAC) for labeling biomolecules, developing diagnostic probes, or creating antibody-drug conjugates (ADCs).
• Chemical Biology Tool: Serves as a precursor for synthesizing chemical probes to study enzyme function or protein-protein interactions within biological systems.
• Material Science Research: Potential use as a monomer or cross-linker in the development of specialty polymers and advanced materials with tailored properties.
• Agrochemical Synthesis: An intermediate in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	2-(Prop-2-Yn-1-Yloxy)Ethan-1-Amine Hydrochloride
CAS No.	1383604-96-3
Molecular Formula	C5H10ClNO
Molecular Weight	135.59 g/mol
Synonyms	2-(Prop-2-yn-1-yloxy)ethan-1-amine hydrochloride; 2-(Prop-2-ynyloxy)ethylamine hydrochloride; 2-(Prop-2-yn-1-yloxy)ethylamine HCl; 2-(Prop-2-ynyloxy)ethanamine hydrochloride; 2-(2-Propynyloxy)ethylamine hydrochloride; Propargyloxyethylamine hydrochloride; N-(2-Propynyloxy)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Prop-2-Yn-1-Yloxy)Ethan-1-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.