Description

Ethyl 5-Bromoquinoline-3-Carboxylate is a high-purity brominated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in developing new crop protection agents and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a precursor for organic semiconductors, ligands for metal-organic frameworks (MOFs), and photoactive compounds.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for constructing fused heterocyclic systems.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological studies and discovery chemistry projects.

Basic Information

Product Name	Ethyl 5-Bromoquinoline-3-Carboxylate
CAS No.	1383551-36-7
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	5-Bromoquinoline-3-carboxylic acid ethyl ester; Ethyl 5-bromo-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 5-bromo-, ethyl ester; 5-Bromo-3-quinolinecarboxylic acid ethyl ester; Ethyl 5-bromoquinoline-3-carboxylate; 1383551-36-7; 5-Bromoquinoline-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.