Description

(4Ar,7Ar)-4-Methyloctahydropyrrolo[3,4-B][1,4]Oxazine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its bicyclic heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients requiring its specific fused ring system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	(4Ar,7Ar)-4-Methyloctahydropyrrolo[3,4-B][1,4]Oxazine Dihydrochloride
CAS No.	1383453-67-5
Molecular Formula	C8H17Cl2N2O
Molecular Weight	228.14 g/mol
Synonyms	4-Methyloctahydropyrrolo[3,4-b][1,4]oxazine dihydrochloride; (4aR,7aR)-4-Methylhexahydro-1H-pyrrolo[3,4-b][1,4]oxazine dihydrochloride; 1383453-67-5; (4aR,7aR)-4-Methyloctahydro-2H-pyrrolo[3,4-b][1,4]oxazine dihydrochloride; 4-Methyl-4a,5,6,7,7a,8-hexahydro-2H-pyrrolo[3,4-b][1,4]oxazine dihydrochloride
EINECS	Contact for details

Quality Control

Our (4Ar,7Ar)-4-Methyloctahydropyrrolo[3,4-B][1,4]Oxazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.