Description

5-Bromo-2-(trifluoromethoxy)cinnamic acid is a high-purity, multi-functional chemical intermediate designed for advanced synthesis. This compound is valued for its unique molecular architecture, which combines bromine and trifluoromethoxy substituents on a cinnamic acid backbone, enabling precise modifications in complex molecular frameworks. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate in the production of specialty electronic chemicals for display and lighting technologies.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D labs for constructing complex organic molecules, studying structure-activity relationships (SAR), and developing new synthetic methodologies.
• Fluorinated Compound Library Development: A valuable scaffold for creating libraries of fluorinated compounds in discovery chemistry for high-throughput screening.

Basic Information

Product Name	5-Bromo-2-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1381952-88-0
Molecular Formula	C10H6BrF3O3
Molecular Weight	311.06 g/mol
Synonyms	(E)-3-[5-Bromo-2-(trifluoromethoxy)phenyl]acrylic acid; 5-Bromo-2-(trifluoromethoxy)benzeneacrylic acid; 3-(5-Bromo-2-(trifluoromethoxy)phenyl)-2-propenoic acid; (2E)-3-[5-Bromo-2-(trifluoromethoxy)phenyl]prop-2-enoic acid; 5-Bromo-α-(trifluoromethoxy)cinnamic acid; 5-Bromo-2-(trifluoromethoxy)cinnamate
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(trifluoromethoxy)cinnamic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with complete batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.