Description

(R)-2-(o-Tolyl)Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and metabolic disorder therapeutics. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers serving the life sciences sector.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of advanced drug candidates.
• Asymmetric Catalysis Research: Used as a ligand precursor or a chiral auxiliary in developing new catalytic systems.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Chemical Biology: Utilized in the design and synthesis of molecular probes for biological target identification.

Basic Information

Product Name	(R)-2-(o-Tolyl)Pyrrolidine Hydrochloride
CAS No.	1381929-14-1
Molecular Formula	C11H15N·HCl
Molecular Weight	197.71 g/mol
Synonyms	(R)-2-(2-Methylphenyl)pyrrolidine hydrochloride; (R)-2-o-Tolylpyrrolidine hydrochloride; (R)-α-Methyl-2-pyrrolidinemethanol hydrochloride (related); Pyrrolidine, 2-(2-methylphenyl)-, (2R)-, hydrochloride; (2R)-2-(2-Methylphenyl)pyrrolidin-1-ium chloride
EINECS	Contact for details

Quality Control

Our (R)-2-(o-Tolyl)Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.