Description

3-((2S)Pyrrolidin-2-Yl)Benzoic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in the stereochemical integrity of the (2S)-pyrrolidine moiety, which is crucial for imparting specific biological activity in target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical building block in multi-step synthetic routes for complex target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric transformations.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical assays.

Basic Information

Product Name	3-((2S)Pyrrolidin-2-Yl)Benzoic Acid Hydrochloride
CAS No.	1381927-59-8
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	(S)-2-(3-Carboxyphenyl)pyrrolidine hydrochloride; Benzoic acid, 3-[(2S)-2-pyrrolidinyl]-, hydrochloride; 3-[(2S)-Pyrrolidin-2-yl]benzoic acid hydrochloride; (S)-3-(Pyrrolidin-2-yl)benzoic acid HCl; 1381927-59-8; (2S)-2-(3-Carboxyphenyl)-1-pyrrolidinium chloride
EINECS	Contact for details

Quality Control

Our 3-((2S)Pyrrolidin-2-Yl)Benzoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.