Description

4-(3-Methoxyphenyl)Oxan-4-Amine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role in the synthesis of more complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique scaffold combining a methoxyphenyl group with a tetrahydropyranyl amine.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its aromatic and heterocyclic structure.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and advanced materials requiring specific chiral or structural motifs.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental organic synthesis projects and methodological development.
• Contract Research and Manufacturing (CRO/CMO): A critical raw material for organizations providing custom synthesis and scale-up services to the life sciences industry.

Basic Information

Product Name	4-(3-Methoxyphenyl)Oxan-4-Amine Hydrochloride
CAS No.	1380300-46-8
Molecular Formula	C12H18ClNO2
Molecular Weight	243.73 g/mol
Synonyms	4-(3-Methoxyphenyl)tetrahydro-2H-pyran-4-amine hydrochloride; 4-Amino-4-(3-methoxyphenyl)tetrahydro-2H-pyran hydrochloride; 4-(3-Methoxyphenyl)-4-aminotetrahydropyran hydrochloride; 3-Methoxy-α-(4-piperidyl)benzyl alcohol hydrochloride (related); THP-protected 3-methoxyphenyl amine hydrochloride; 4-(m-Anisyl)-4-aminotetrahydropyran hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(3-Methoxyphenyl)Oxan-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.