Description

{4-[(4-Methoxyphenyl)Methyl]Oxan-4-Yl}Methanamine Hydrochloride is a high-purity, synthetic organic compound supplied as its hydrochloride salt for enhanced stability and handling. This specialized intermediate is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or metabolic disorder targets.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its unique tetrahydropyran and anisylmethylamine scaffold.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Agrochemical Synthesis: Potential intermediate in the development of new herbicides or fungicides, leveraging its aromatic ether and amine functionality.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying enzyme function or receptor interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular architecture.

Basic Information

Product Name	{4-[(4-Methoxyphenyl)Methyl]Oxan-4-Yl}Methanamine Hydrochloride
CAS No.	1380300-43-5
Molecular Formula	C14H22ClNO2
Molecular Weight	271.78 g/mol
Synonyms	4-[(4-Methoxyphenyl)methyl]tetrahydro-2H-pyran-4-methanamine hydrochloride; 4-(4-Methoxybenzyl)tetrahydro-2H-pyran-4-ylmethanamine HCl; (4-(4-Methoxybenzyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride; 1-(4-Methoxyphenyl)-1-(tetrahydro-2H-pyran-4-yl)methanamine hydrochloride; 4-(4-Methoxybenzyl)tetrahydropyran-4-ylmethylamine hydrochloride; 4-(p-Methoxybenzyl)-4-(aminomethyl)tetrahydropyran hydrochloride; 1380300-43-5 (CAS Name)
EINECS	Contact for details

Quality Control

Our {4-[(4-Methoxyphenyl)Methyl]Oxan-4-Yl}Methanamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.