Description

Ethyl 5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-A][1,3]Diazepine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolodiazepine chemical class. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with potential activity in the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel psychotropic and neuroactive drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: A crucial building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially for CNS disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and diazepine derivatives.
• Pre-clinical Development: Employed in the production of compounds for pharmacological screening and pre-clinical testing phases.

Basic Information

Product Name	Ethyl 5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-A][1,3]Diazepine-3-Carboxylate
CAS No.	1380300-40-2
Molecular Formula	C11H14N4O2
Molecular Weight	234.26 g/mol
Synonyms	Ethyl [1,2,4]triazolo[4,3-a][1,3]diazepine-3-carboxylate; 3-Carbethoxy-5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a][1,3]diazepine; Ethyl 1,2,4-triazolo[4,3-a][1,3]diazepine-3-carboxylate; 1380300-40-2; Triazolodiazepine-3-carboxylic acid ethyl ester; Fused triazolodiazepine derivative; 3-(Ethoxycarbonyl)-5,6,7,8,9-pentahydro-[1,2,4]triazolo[4,3-a][1,3]diazepine
EINECS	Contact for details

Quality Control

Our Ethyl 5H,6H,7H,8H,9H-[1,2,4]Triazolo[4,3-A][1,3]Diazepine-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes rigorous analytical testing including HPLC, NMR, and MS for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.