Description

[4-(2-Bromophenyl)Oxan-4-Yl]Methanamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its unique molecular scaffold, which incorporates both a brominated aromatic ring and a tetrahydro-2H-pyran moiety, making it a versatile synthon for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small molecule drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its functionalized bromophenyl and amine hydrochloride groups.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Acts as a starting material for creating molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses producing specialized compounds for client projects.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	[4-(2-Bromophenyl)Oxan-4-Yl]Methanamine Hydrochloride
CAS No.	1380300-38-8
Molecular Formula	C12H16BrNO•HCl
Molecular Weight	306.63 g/mol (Free base: 270.17 g/mol)
Synonyms	1-((2-Bromophenyl)(tetrahydro-2H-pyran-4-yl)methyl)methanamine hydrochloride; (4-(2-Bromophenyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride; 1-(2-Bromophenyl)-1-(tetrahydro-2H-pyran-4-yl)methanamine HCl; 4-(2-Bromophenyl)tetrahydro-2H-pyran-4-ylmethanamine hydrochloride; (4-(2-Bromophenyl)tetrahydro-2H-pyran-4-yl)methylamine hydrochloride; 1380300-38-8; 4-(2-Bromophenyl)oxan-4-ylmethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our [4-(2-Bromophenyl)Oxan-4-Yl]Methanamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.