Description

2,5-Dihydro-3-(Hydroxymethyl)-2,2,5,5-Tetramethyl-4-(3-Pyridinyl)-1H-Pyrrol-1-Yloxy is a specialized pyrrolidine derivative featuring a nitroxyl radical and a pyridinyl substituent, making it a valuable intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel materials and pharmaceuticals, particularly where controlled radical chemistry or spin-labeling is required. Industries such as pharmaceutical R&D, agrochemical development, and specialty polymer manufacturing need this high-purity intermediate for creating next-generation products.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Spin-Labeling Agent: Used in Electron Paramagnetic Resonance (EPR) spectroscopy for studying protein dynamics, membrane fluidity, and macromolecular structure.
• Polymerization Modifier: Acts as a nitroxide mediator in controlled/living radical polymerization (NMP) to produce polymers with precise molecular weights and architectures.
• Agrochemical Synthesis: Employed as a building block for developing advanced crop protection agents with novel modes of action.
• Material Science Research: Utilized in the development of organic magnetic materials, conductive polymers, and other functional materials.
• Bioconjugation Chemistry: Facilitates the site-specific labeling of biomolecules (proteins, nucleic acids) for diagnostic and research applications.

Basic Information

Product Name	2,5-Dihydro-3-(Hydroxymethyl)-2,2,5,5-Tetramethyl-4-(3-Pyridinyl)-1H-Pyrrol-1-Yloxy
CAS No.	1379779-17-5
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	3-Pyridinyl-TEMPO hydroxymethyl derivative; 4-(3-Pyridinyl)-2,2,5,5-tetramethyl-3-(hydroxymethyl)-2,5-dihydro-1H-pyrrol-1-yloxy; 1-Oxy-2,2,5,5-tetramethyl-3-(hydroxymethyl)-4-(3-pyridinyl)-2,5-dihydro-1H-pyrrole; 3-Pyridyl-TEMPO-CH2OH; Pyridinyl-substituted nitroxyl radical; 4-(Pyridin-3-yl)-TEMPO methanol; 3-Hydroxymethyl-2,2,5,5-tetramethyl-4-(3-pyridyl)-pyrrolidine-1-oxyl
EINECS	Contact for details

Quality Control

Our 2,5-Dihydro-3-(Hydroxymethyl)-2,2,5,5-Tetramethyl-4-(3-Pyridinyl)-1H-Pyrrol-1-Yloxy is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting R&D and production standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame. The container must be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.