Description

2-Bromo-1-(2,2-Diethoxyethoxy)-4-Methylbenzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique brominated aromatic structure with a protected diethoxyethoxy side chain. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where its reactive bromine site and protected functional group enable precise molecular construction. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its aromatic halogen functionality.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors and functional polymers due to its tailored aromatic core.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs to produce bespoke molecules for client projects.
• Academic Research: A valuable reagent for methodological studies in organic chemistry, exploring new cross-coupling and functionalization reactions.

Basic Information

Item	Details
Product Name	2-Bromo-1-(2,2-Diethoxyethoxy)-4-Methylbenzene
CAS No.	1379658-80-6
Molecular Formula	C13H19BrO3
Molecular Weight	303.19 g/mol
Synonyms	1-Bromo-2-(2,2-diethoxyethoxy)-5-methylbenzene; 4-Methyl-2-bromophenoxyacetaldehyde diethyl acetal; 2-Bromo-4-methylphenoxyacetaldehyde diethyl acetal; (2-Bromo-4-methylphenoxy)acetaldehyde diethyl acetal; 2-(2-Bromo-5-methylphenoxy)-1,1-diethoxyethane; 1379658-80-6; 2-Bromo-1-(2,2-diethoxyethoxy)-4-methyl-benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(2,2-Diethoxyethoxy)-4-Methylbenzene is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Our quality control protocols are designed to guarantee batch-to-batch reliability for your critical synthesis workflows. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.