Description

Ethyl 2-Bromo-4-Chloroquinoline-3-Carboxylate is a high-purity, multi-functional quinoline derivative serving as a critical synthetic building block in advanced organic chemistry. Its value lies in its versatile reactivity, enabling the construction of complex heterocyclic scaffolds essential for pharmaceutical and agrochemical discovery. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing quinoline-based therapeutics with potential antimicrobial, anticancer, or anti-inflammatory activity.
• Agrochemical Research: Used to construct complex heterocyclic cores for new generations of herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline moiety.
• Material Science: Serves as a building block for creating organic semiconductors, luminescent materials, or metal-organic frameworks (MOFs) due to its electron-rich aromatic system and halogen substituents for further functionalization.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions, where the bromo and chloro groups offer orthogonal reactivity for sequential derivatization.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new reaction pathways in academic laboratories and contract research organizations (CROs).

Basic Information

Product Name	Ethyl 2-Bromo-4-Chloroquinoline-3-Carboxylate
CAS No.	1379615-56-1
Molecular Formula	C₁₂H₉BrClNO₂
Molecular Weight	314.56 g/mol
Synonyms	2-Bromo-4-chloroquinoline-3-carboxylic acid ethyl ester; Ethyl 2-bromo-4-chloro-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 2-bromo-4-chloro-, ethyl ester; 2-Bromo-4-chloro-quinoline-3-carboxylic acid ethyl ester; 1379615-56-1; Ethyl 2-bromo-4-chloroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-4-Chloroquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.