Description

5-Bromo-3-Iodo-2-Methylbenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where it enables precise structural modifications and the introduction of halogen atoms to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and diagnostic agents.
• Cross-Coupling Reactions: Valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the bromo and iodo substituents.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-3-Iodo-2-Methylbenzoic Acid
CAS No.	1379364-28-9
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	2-Methyl-5-bromo-3-iodobenzoic acid; 5-Bromo-3-iodo-o-toluic acid; Benzoic acid, 5-bromo-3-iodo-2-methyl-; 2-Methyl-3-iodo-5-bromobenzoic acid; 3-Iodo-5-bromo-2-methylbenzoic acid; 5-Bromo-3-iodo-2-methyl-benzoic acid; 1379364-28-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-2-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.