Description

6'-Bromospiro[Cyclopropane-1,3'-Indoline] is a high-value, spirocyclic organic building block featuring a brominated indoline fused to a cyclopropane ring. This unique molecular architecture makes it a critical intermediate for medicinal chemistry research and the development of novel pharmaceutical compounds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex, three-dimensional molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in programs targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its spirocyclic and halogenated properties.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or insecticidal activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Material Science: Potential precursor for organic electronic materials or ligands in catalytic systems, leveraging its rigid, three-dimensional structure.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological development and exploratory synthetic chemistry.

Basic Information

Product Name	6'-Bromospiro[Cyclopropane-1,3'-Indoline]
CAS No.	1379360-39-0
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	6'-Bromo-1'H-spiro[cyclopropane-1,3'-indoline]; 6'-Bromospiro[cyclopropane-1,3'-indoline]; Spiro[cyclopropane-1,3'-indoline], 6'-bromo-; 6'-Bromo-1'H-spiro[cyclopropane-1,3'-indole]; 6'-Bromospiro(cyclopropane-1,3'-indoline); 6'-Bromo-spiro(cyclopropane-1,3'-indoline)
EINECS	Contact for details

Quality Control

Our 6'-Bromospiro[Cyclopropane-1,3'-Indoline] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.