Description

{[3-(Bromomethyl)Cyclobutoxy]Methyl}Benzene is a specialized brominated cyclobutane derivative, a high-value building block in advanced organic synthesis. Its molecular architecture, featuring a reactive bromomethyl group and a benzyl-protected cyclobutoxy moiety, makes it a critical intermediate for constructing complex, strained-ring systems. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals with specific optical or mechanical properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme function and protein interactions.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.

Basic Information

Product Name	{[3-(Bromomethyl)Cyclobutoxy]Methyl}Benzene
CAS No.	1379358-84-5
Molecular Formula	C13H17BrO
Molecular Weight	269.18 g/mol
Synonyms	1-[(3-Bromomethylcyclobutoxy)methyl]benzene; Benzyl 3-(bromomethyl)cyclobutyl ether; (3-Bromomethyl-cyclobutoxymethyl)-benzene; α-[(3-Bromomethylcyclobutoxy)methyl]toluene; Cyclobutane, 1-(bromomethyl)-3-[(phenylmethoxy)methyl]-; 3-(Bromomethyl)cyclobutyl benzyl ether
EINECS	Contact for details

Quality Control

Every batch of {[3-(Bromomethyl)Cyclobutoxy]Methyl}Benzene is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.