Description

Benzyl 3-Nitroazetidine-1-Carboxylate CAS NO 1379079-50-1 is a high-purity, protected azetidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex nitrogen-containing heterocycles, which are central to modern pharmaceutical discovery and materials science. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel azetidine-based drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used to construct bioactive scaffolds for the development of new herbicides, fungicides, and insecticides.
• Chemical Biology Probe Synthesis: Serves as a versatile handle for creating molecular probes to study enzyme function and biological pathways.
• Peptidomimetics & Constrained Peptides: Incorporated to introduce conformational rigidity into peptide backbones, enhancing stability and bioavailability.
• Ligand & Catalyst Development: Utilized in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or functionalization agent for creating polymers with specific nitrogen-rich functionalities.

Basic Information

Product Name	Benzyl 3-Nitroazetidine-1-Carboxylate
CAS No.	1379079-50-1
Molecular Formula	C11H12N2O4
Molecular Weight	236.23 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3-nitroazetidine; Benzyl 3-Nitroazetidine-1-carboxylate; 3-Nitroazetidine-1-carboxylic Acid Benzyl Ester; 1-CBz-3-Nitroazetidine; Azetidine-1-carboxylic acid, 3-nitro-, benzyl ester; 1-(Benzyloxycarbonyl)-3-nitroazetidine; 3-Nitro-1-azetidinecarboxylic Acid Phenylmethyl Ester
EINECS	Contact for details

Quality Control

Our Benzyl 3-Nitroazetidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.