Description

6'-Fluorospiro[Cyclopropane-1,3'-Indolin]-2'-One is a high-value, fluorinated spirocyclic oxindole building block of significant interest in advanced organic synthesis. This compound matters for its unique three-dimensional structure and the presence of a fluorine atom, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients. The CAS number for this compound is 1378834-16-2.

Application

This versatile fluorinated spiro scaffold is designed for sophisticated molecular construction in several high-value sectors.

• Pharmaceutical Intermediate: Serves as a privileged core structure in medicinal chemistry for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the discovery of novel herbicides, fungicides, and insecticides, where the spirocyclic and fluorine motifs can enhance bioactivity and environmental stability.
• Chemical Biology Probe Development: Employed to create tool compounds for studying enzyme function and protein-protein interactions within biological systems.
• Material Science Precursor: Acts as a specialized monomer or building block for developing advanced organic materials with specific electronic or optical properties.

Basic Information

Product Name	6'-Fluorospiro[Cyclopropane-1,3'-Indolin]-2'-One
CAS No.	1378834-16-2
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	6'-Fluoro-1'H-spiro[cyclopropane-1,3'-indol]-2'(2'H)-one; 6-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one; 6'-Fluorospiro(cyclopropane-1,3'-indolin)-2'-one; Spiro[cyclopropane-1,3'-indolin]-2'-one, 6'-fluoro-; 1378834-16-2
EINECS	Contact for details

Quality Control

Our 6'-Fluorospiro[Cyclopropane-1,3'-Indolin]-2'-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and should be handled under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.