Description

4-Bromo-6-Fluoro-8-Methyl-Quinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that need it include pharmaceutical R&D for creating novel active pharmaceutical ingredients (APIs), agrochemical research for new crop protection agents, and academic institutions engaged in materials science and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a building block for creating organic light-emitting diodes (OLEDs) and other functional organic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes.
• Academic & Contract Research: A valuable reagent for method development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	4-Bromo-6-Fluoro-8-Methyl-Quinoline
CAS No.	1378255-46-9
Molecular Formula	C10H7BrFN
Molecular Weight	240.07 g/mol
Synonyms	8-Methyl-4-bromo-6-fluoroquinoline; 6-Fluoro-8-methyl-4-bromoquinoline; 4-Bromo-6-fluoro-8-methylquinoline; Quinoline, 4-bromo-6-fluoro-8-methyl-; 1378255-46-9; 4-Br-6-F-8-Me-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Fluoro-8-Methyl-Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.